What are the thrombolytic treatments for acute myocardial infarction?


Acute myocardial infarction is a type of ischemic heart disease in which patients will experience symptoms such as severe chest pain and difficulty breathing. Thrombolytic therapy refers to the infusion of intravenous drugs to dissolve blood clots blocking blood vessels and restore the patency of coronary arteries, thereby saving ischemic myocardial tissue.

Thrombolytic therapy is suitable for the following situations: the first is within 12 hours of symptom onset; the second is when emergency echocardiography shows prolonged left ventricular end-systolic and end-diastolic filling times, and the filling time is estimated to be 30 minutes after thrombolysis It can be shortened to normal; the third is that coronary angiography shows that the length of the lesion is less than 30% of the proximal left main trunk or less than 75% of the proximal left anterior descending artery; the fourth is that all patients without contraindications to thrombolysis can undergo thrombolytic treatment; The fifth method is that when the indication for interventional surgery is clear but timely intervention cannot be performed, thrombolysis can also be performed first.

Commonly used thrombolytic drugs include urokinase, recombinant streptokinase, etc. Before using these drugs, the patient’s coagulation function, renal function and other indicators need to be evaluated, and bleeding tendencies and other contraindications need to be ruled out.

It should be noted that thrombolytic treatment has certain risks and may lead to complications such as intracranial hemorrhage and gastrointestinal bleeding. Therefore, when deciding whether to perform thrombolytic treatment, doctors will comprehensively consider the patient’s condition, physical condition, and possible risk factors to formulate a personalized treatment plan. At the same time, monitoring after thrombolysis is also very important, including closely monitoring changes in vital signs such as blood pressure, heart rate, and oxygen saturation, so that possible problems can be discovered and dealt with in a timely manner.

In short, thrombolytic therapy is an effective treatment method, but care must be taken during its implementation and the indications and contraindications must be strictly controlled to ensure safe and effective treatment of patients with acute myocardial infarction.



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