What is medulloblastoma? What are the clinical symptoms?

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Medulloblastoma accounts for 1.84%-6.54% of intracranial tumors . It is a malignant glioma of the posterior cranial fossa. The onset site is the brain and is non-infectious. Medulloblastoma mainly affects children, followed by young people.

According to relevant data, the number of patients under 20 years old accounts for 88.51% of the total number of patients, the number of patients under 10 years old accounts for 50.71% of the total number of patients, and the number of patients between 21-40 years old accounts for 50.71% of the total number of patients. 10.23% of the patients, and the number of patients aged 41-60 accounted for 1.26% of the total number of patients.

Medulloblastoma is highly malignant and has clear boundaries. The tumor is soft, purple-red or gray-red, and looks like jam. This is because the tumor is rich in cells and blood vessels. Tumors tend to invade the leptomeninges. The meninges are infiltrated and cause proliferation, making the tumor cell tissue elastic and hard. The tendency to infiltrate the leptomeninges can lead to invasive metastasis to the subarachnoid and ventricular systems. Necrosis can occur in the center of the tumor, but it is rare.

As the tumor continues to grow, symptoms appear and become more and more obvious. Common symptoms include nausea and vomiting, headache, and papilledema, which are caused by increased intracranial pressure. They appear in the morning and are relieved after eating. If left untreated, symptoms may also occur at night and interfere with sleep. In addition, symptoms such as vision loss, facial paralysis, and double vision will gradually appear. If the tumor metastasizes and involves nearby organs or tissues, other complications may occur.

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